Home Chemistry Heterocyclic Building Blocks Pyrrolidines 6-Azaspiro[3.4]Octane
Nucleophilic Substitution: The nitrogen atom in the spirocyclic ring can act as a nucleophile and undergo substitution reactions with electrophiles. For example, it can react with alkyl halides to form alkyl-substituted derivatives of the compound.
Oxidation: 6-azaspiro[3.4]octane can potentially undergo oxidation reactions, depending on the reaction conditions. Oxidizing agents like potassium permanganate or chromic acid could oxidize the compound, introducing functional groups such as amines or ketones.
Acylation and Alkylation: The compound can undergo acylation and alkylation reactions with appropriate reagents to introduce acyl or alkyl groups onto the nitrogen atom.
Ring Opening Reactions: Depending on the conditions, 6-azaspiro[3.4]octane may undergo ring-opening reactions, potentially leading to the formation of linear or branched compounds.
Cycloaddition Reactions: In the presence of suitable reactants, it might participate in cycloaddition reactions, such as Diels-Alder reactions, to form more complex cyclic compounds.
Protonation: The nitrogen atom in the spirocyclic ring can also be protonated under acidic conditions, leading to the formation of protonated species.
Rearrangements: Depending on the reaction conditions and the presence of other functional groups, rearrangement reactions may occur.
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tert-Butyl 2-hydroxy-6-azaspiro[3.4]octane-6-carboxylate
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tert-butyl 2-amino-6-azaspiro[3.4]octane-6-carboxylate
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tert-butyl 2-formyl-6-azaspiro[3.4]octane-6-carboxylate
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8,8-Difluoro-6-azaspiro[3.4]octane hydrochloride
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